How genetic differences affect the gut bacteria in monkeys
Host genetic variation affecting the microbiome in rhesus macaques
This study is looking at how genes affect the bacteria living in the guts, mouths, and noses of rhesus macaques, which could help us learn more about how these bacteria relate to health issues in humans.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Mississippi Med Ctr NIH-funded |
| Lab location | 1 site (Jackson, United States) |
| Project ID | NIH-10448419 on NIH RePORTER |
What this research studies
This research investigates how genetic variations influence the microbiome, which is the collection of bacteria in the gut, mouth, and nose, in rhesus macaques. By studying 1300 monkeys from different colonies, the researchers aim to understand the differences in microbiome composition among individuals. They will also conduct genome-wide studies to link specific genetic traits to variations in microbiome diversity and bacterial types. This work could help establish the rhesus macaque as a valuable model for understanding human microbiome-related diseases.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research would include individuals with conditions linked to microbiome imbalances, such as obesity, diabetes, or psychiatric disorders.
Not a fit: Patients with no interest in microbiome research or those not affected by the conditions being studied may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into how the microbiome affects various diseases, potentially improving treatment strategies for conditions like obesity, diabetes, and mental health disorders.
How similar studies have performed: Other research has shown promising results in linking microbiome variations to health outcomes, suggesting that this approach could yield valuable insights.
Where this research is happening
Jackson, United States
- University of Mississippi Med Ctr — Jackson, United States (Active)
Researchers
- Principal investigator: Vallender, Eric J. — University of Mississippi Med Ctr
- Study coordinator: Vallender, Eric J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.