How genetic and environmental factors influence differences in traits among species and sexes
Official title: Genetic mechanisms of phenotypic variation within and amongst genotypes, environments, and sexes
Funded at University of Houston · NIH-11016981 · Data updated 2026-11-12
This study is looking at how genes, gender, and the environment affect differences in traits among fruit flies and house flies, which could help us understand the genetic reasons behind variations in how living things respond to infections, and this knowledge might lead to better treatments for human diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $353,250 |
| NIH project number | 5R35GM152232-02 |
| Project ID | NIH-11016981 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with genetic conditions or those affected by bacterial infections.
✕Less likely to help
Patients with conditions unrelated to genetic variation or bacterial infections may not receive direct benefits from this research.
What this research studies
This research investigates how genetic variation, sex differences, and environmental factors contribute to differences in traits within and between species. By studying organisms like fruit flies and house flies, the research aims to uncover the genetic mechanisms that lead to variations in traits, including responses to bacterial infections. The project combines experimental and genomic methods to explore these interactions, which could provide insights into the biological basis of many human diseases. Understanding these mechanisms is crucial for developing targeted treatments and interventions.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of genetic diseases and better treatment strategies for infections and other health conditions.
How similar studies have gone: Other research has shown success in understanding genetic mechanisms and their impact on health, making this approach promising and relevant.
Where this research is happening
-
University of Houston
Houston, United States Active
Researchers
- Principal investigator: Meisel, Richard P. — University of Houston
- Study coordinator: Meisel, Richard P.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.