How genes affect obsessive-compulsive disorder in people of Latin American ancestry
Official title: 2/2 TRANS-ANCESTRY GENOMIC ANALYSIS OF OBSESSIVE COMPULSIVE DISORDER
Funded at Baylor College of Medicine · NIH-11381494 · Data updated 2026-11-12
This project looks at how genetic differences influence OCD risk in people with Latin American ancestry.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 17, 2021 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $10,000 |
| NIH project number | 3U01MH125062-05S1 |
| Project ID | NIH-11381494 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with a clinical diagnosis of OCD who are of Latin American ancestry or have roots in Latin American countries would be the best fit to participate.
✕Less likely to help
People without OCD or those from ancestries not represented in the study may not directly benefit from this specific project.
What this research studies
You would be part of a large effort to collect genetic and clinical information from about 5,000 people with OCD from Latin America, with some participants recruited in the U.S. and online. Clinics in a regional network will gather detailed symptom information, other mental health diagnoses, and clinical histories. Blood or saliva samples will be genotyped so researchers can search across ancestries for genetic variants linked to OCD. The goal is to expand diversity in OCD genomics so findings apply more broadly and point to biological pathways for future treatments.
Why it matters
Potential benefit: If successful, this work could reveal biological causes of OCD that lead to better detection methods and more targeted, personalized treatments over time.
How similar studies have gone: Similar large-scale genomic approaches have produced important discoveries in schizophrenia, bipolar disorder, and autism, while trans-ancestry OCD genomics is newer but promising.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Storch, Eric a. — Baylor College of Medicine
- Study coordinator: Storch, Eric a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.