How genes affect Crohn's disease and ulcerative colitis in South Florida
University of Miami IBD Genetic Research Center: Understanding the Genetic Architecture of IBD in the South Florida community
This project looks at genetic and environmental factors linked to Crohn's disease and ulcerative colitis in South Florida patients, with special focus on Hispanic and immigrant communities.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11286115 on NIH RePORTER |
What this research studies
You would be asked to share medical history and biological samples so researchers can compare genes, clinical features, and possibly microbiome patterns between groups. The team focuses on Latin-American immigrants and American-born Hispanic patients to understand why IBD rates are rising in these communities. Researchers will link genetic data to disease characteristics and treatment histories to find patterns that explain disparities. The goal is to build knowledge that could guide prevention and better-tailored care for people with IBD in South Florida.
Who could benefit from this research
Good fit: Ideal participants are people with Crohn's disease or ulcerative colitis living in South Florida, especially Hispanic or Latin-American immigrants and American-born Hispanic patients.
Not a fit: People without IBD or those living far outside the South Florida region are unlikely to receive direct benefits from this project in the short term.
Why it matters
Potential benefit: If successful, this work could help tailor prevention and treatment approaches for IBD in Hispanic and immigrant populations.
How similar studies have performed: Previous genetic and microbiome studies have identified IBD risk genes and patterns, and this group has published influential work on IBD in Hispanic populations, supporting this approach.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Mccauley, Jacob L — University of Miami School of Medicine
- Study coordinator: Mccauley, Jacob L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.