How gender and hormones affect recovery from cannabis use disorder

Gender and Sex Hormone Influences on Cannabis Use Disorder Remission

['FUNDING_R01'] · MEDICAL UNIVERSITY OF SOUTH CAROLINA · NIH-10844358

This study is looking at how gender and hormones affect how well people recover from cannabis use disorder, aiming to find better treatment options for both men and women.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMEDICAL UNIVERSITY OF SOUTH CAROLINA (nih funded)
Locations1 site (CHARLESTON, UNITED STATES)
Trial IDNIH-10844358 on ClinicalTrials.gov

What this research studies

This research investigates how gender and sex hormones influence the remission of cannabis use disorder (CUD). It aims to understand the differences in treatment responses between men and women, particularly focusing on the role of ovarian hormones in drug sensitivity and behavior. The study will explore whether different treatment endpoints are needed for men and women and assess the effectiveness of reducing cannabis use as a viable alternative to complete abstinence. By examining these factors, the research seeks to improve treatment strategies for individuals struggling with CUD.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing cannabis use disorder.

Not a fit: Patients who do not have cannabis use disorder or are under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective, gender-specific treatment options for cannabis use disorder.

How similar studies have performed: Other research has shown success in exploring gender differences in addiction treatment, suggesting that this approach could yield valuable insights.

Where this research is happening

CHARLESTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: ethanol use disorder, alcohol use disorder, Mental health disorders, Psychiatric Disease, Psychiatric Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.