NIH-funded research R01 grant

How gender and hormones affect recovery from cannabis use disorder

Official title: Gender and Sex Hormone Influences on Cannabis Use Disorder Remission

Funded at Medical University of South Carolina · NIH-10844358 · Data updated 2026-11-12

This study is looking at how gender and hormones affect how well people recover from cannabis use disorder, aiming to find better treatment options for both men and women.

More Cannabis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startJuly 1, 2021
Project endNovember 30, 2025
Funding year2024
Award (this year)$397,185
NIH project number5R01DA054617-04
Project IDNIH-10844358 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who are experiencing cannabis use disorder.

Less likely to help

Patients who do not have cannabis use disorder or are under 21 years old may not benefit from this research.

What this research studies

This research investigates how gender and sex hormones influence the remission of cannabis use disorder (CUD). It aims to understand the differences in treatment responses between men and women, particularly focusing on the role of ovarian hormones in drug sensitivity and behavior. The study will explore whether different treatment endpoints are needed for men and women and assess the effectiveness of reducing cannabis use as a viable alternative to complete abstinence. By examining these factors, the research seeks to improve treatment strategies for individuals struggling with CUD.

Why it matters

Potential benefit: If successful, this research could lead to more effective, gender-specific treatment options for cannabis use disorder.

How similar studies have gone: Other research has shown success in exploring gender differences in addiction treatment, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Tomko, Rachel Lynn — Medical University of South Carolina
  • Study coordinator: Tomko, Rachel Lynn

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.