NIH-funded research R01 grant

How flies find food by quick turns and sensing the wind

Official title: The Functional Role and Neural Basis of Rapid Turns in Olfactory Search Behavior

Funded at California Institute of Technology · NIH-11401991 · Data updated 2026-11-12

Researchers are studying how fruit flies use fast directional turns and wind information to search for food, which could inform how brains guide movement in uncertain environments.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCalifornia Institute of Technology
NIH-funded
Lab location1 site (Pasadena, United States)
Project startSeptember 5, 2024
Project endAugust 31, 2029
Funding year2026
Award (this year)$1,035,153
NIH project number5R01NS136988-03
Project IDNIH-11401991 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to patients; this study involves animal behavior and neural mechanisms.

Less likely to help

No direct patient participation or benefit in this study.

What this research studies

This project examines how animals use deliberate turns to gather information about their surroundings when searching for food. By studying fruit flies and their rapid body turns during flight, the team will link wind direction, wind speed, and altitude to decision-making in movement. They will combine advanced imaging, genetics, and connectome data to understand the neural basis of these behaviors. The work aims to reveal how internal and external states shape where an animal goes next.

Why it matters

Potential benefit: Gaining insights into basic brain mechanisms of navigation could inform treatments for human balance and movement disorders in the long term.

How similar studies have gone: Similar work with model organisms has advanced understanding of sensory-guided movement, though this project proposes a novel integration of observability concepts with fly neuroscience.

Where this research is happening

  • California Institute of Technology
    Pasadena, United States
    Active

Researchers

  • Principal investigator: Dickinson, Michael H — California Institute of Technology
  • Study coordinator: Dickinson, Michael H

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.