How exercise affects aging stem cells
Official title: Impact of Exercise Adaptations on the Aging Stem Cell
Funded at Wichita State University · NIH-10937746 · Data updated 2026-11-12
This study is looking at how regular exercise can help improve the health and function of aging stem cells in the gut and testicles, which could lead to better ways to keep us healthy as we get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wichita State University NIH-funded |
| Lab location | 1 site (Wichita, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $165,982 |
| NIH project number | 1R16GM154750-01 |
| Project ID | NIH-10937746 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults interested in maintaining their health and preventing chronic diseases through lifestyle interventions.
✕Less likely to help
Patients with acute or severe health conditions unrelated to aging or stem cell function may not benefit from this research.
What this research studies
This research investigates how endurance exercise influences the function of aging stem cells, specifically focusing on two types: intestinal stem cells and germline testis stem cells. By using a Drosophila model, the study aims to understand the signaling pathways affected by chronic exercise and how these changes can impact the healthspan, or the period of life free from chronic diseases. The research seeks to clarify the paradoxical effects of aging on these stem cells and how exercise adaptations can potentially restore their function. Patients may benefit from insights that could lead to new interventions for age-related decline in stem cell function.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing healthspan and preventing age-related diseases.
How similar studies have gone: Previous research has shown that exercise can positively influence stem cell function, suggesting that this approach may yield beneficial results.
Where this research is happening
-
Wichita State University
Wichita, United States Active
Researchers
- Principal investigator: Loganathan, Rajprasad — Wichita State University
- Study coordinator: Loganathan, Rajprasad
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.