How dopamine affects learning and behavior
Striatal Dopamine's Role in Associative Learning and Behavior
['FUNDING_FELLOWSHIP'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10824454
This study is looking at how a brain chemical called dopamine helps us learn to connect certain signals with rewards, and it's for anyone interested in understanding how this process works in both people and animals, which could help improve treatments for mental health issues.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10824454 on ClinicalTrials.gov |
What this research studies
This research investigates the role of striatal dopamine in associative learning, which is how we learn to associate cues with rewards. By using tasks that measure how well subjects learn these associations, the study aims to understand how dopamine influences decision-making and learning processes. The research involves both human and rodent models to explore the underlying mechanisms of dopamine's role in these tasks, providing insights that could lead to new treatments for cognitive impairments in psychiatric disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cognitive impairments related to psychiatric conditions.
Not a fit: Patients without cognitive impairments or those not affected by psychiatric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for improving cognitive function in patients with mental health disorders.
How similar studies have performed: Previous research has shown promising results in understanding dopamine's role in learning, suggesting that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DECORTE, BENJAMIN — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: DECORTE, BENJAMIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder, Mental disorders