How dopamine affects behavior and appetite control

Mechanisms of Synaptic Dopamine Signaling in the Control of Behavior

NIH-funded research New York University School of Medicine · NIH-10829398

This study looks at how a brain chemical called dopamine affects behavior and appetite by examining tiny roundworms, which could help us learn more about how dopamine works in people, especially in relation to mental health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10829398 on NIH RePORTER

What this research studies

This research investigates the role of dopamine, a key brain chemical, in regulating behavior and appetite. By studying the microscopic roundworm C. elegans, researchers will explore how dopamine signals are released and processed in response to appetitive stimuli. The study employs advanced molecular genetics and neural circuit analysis techniques to understand how these signals lead to changes in behavior. Insights gained from this research could enhance our understanding of dopamine's role in human mental health disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing mental health disorders or appetite-related issues.

Not a fit: Patients with conditions unrelated to dopamine signaling or those not experiencing mental health or appetite issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments for mental health disorders and conditions related to appetite control.

How similar studies have performed: Previous research has shown promising results in understanding dopamine signaling, suggesting that this approach could yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorderMental disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.