How diet can change gut bacteria in inflammatory bowel disease
Dietary strategies for rational manipulation of the gut microbiome in inflammatory bowel disease
This study is looking at how changing what you eat can help improve gut health for people with inflammatory bowel disease (IBD) by focusing on certain bacteria in your gut that might be causing inflammation, and it will explore new ways to analyze these bacteria to find the best dietary strategies for feeling better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10849816 on NIH RePORTER |
What this research studies
This research investigates how dietary changes can influence the gut microbiome in patients with inflammatory bowel disease (IBD). It aims to develop a new computational method to analyze the metabolic functions of gut bacteria, particularly focusing on sulfur-metabolizing bacteria that may contribute to intestinal inflammation. By understanding these microbial processes, the research seeks to identify dietary strategies that could restore balance in the gut microbiome and improve patient health. Patients may be involved in dietary interventions to assess their effects on gut bacteria and inflammation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with inflammatory bowel disease, including ulcerative colitis and Crohn's disease.
Not a fit: Patients without inflammatory bowel disease or those who do not have any gastrointestinal disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective dietary strategies that help manage or alleviate symptoms of inflammatory bowel disease.
How similar studies have performed: Previous research has shown promise in using dietary interventions to influence gut microbiota, suggesting that this approach may yield beneficial results.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Nguyen, Long H — Massachusetts General Hospital
- Study coordinator: Nguyen, Long H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.