How chronic marijuana use affects blood vessel function

Effects of chronic marijuana use on endothelial function

NIH-funded research University of California, San Francisco · NIH-11077748

This study is looking at how using marijuana regularly and being around others who smoke it might affect heart health, especially how it impacts the blood vessels, to help understand the risks for people who use marijuana or are exposed to its smoke.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11077748 on NIH RePORTER

What this research studies

This research investigates the impact of chronic marijuana use and secondhand exposure on cardiovascular health, particularly focusing on how these factors may lead to endothelial dysfunction, which is a key indicator of vascular health. The study aims to clarify whether the adverse effects observed are due to the cannabinoids in marijuana or the smoke itself. By observing both active users and those exposed to secondhand smoke, the research seeks to fill gaps in current understanding and provide insights into the cardiovascular risks associated with marijuana use.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who are chronic marijuana users or those who have been exposed to secondhand marijuana smoke.

Not a fit: Patients who do not use marijuana and have no exposure to secondhand marijuana smoke are unlikely to benefit from this research.

Why it matters

Potential benefit: If successful, this research could help clarify the cardiovascular risks of marijuana use, potentially leading to better public health guidelines and patient education.

How similar studies have performed: While some studies have explored the effects of tobacco smoke on cardiovascular health, this research is novel in its focus on marijuana and its secondhand smoke effects.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.