How carbohydrate structures affect gut bacteria and health
Carbohydrate Structure Controls on Human Gut Microbial Ecology
This study looks at how the types of carbohydrates we eat affect the good bacteria in our gut, especially for people following a Western diet, and aims to find ways to improve gut health and help prevent diseases like type II diabetes and inflammatory bowel disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project ID | NIH-10645210 on NIH RePORTER |
What this research studies
This research investigates the relationship between different carbohydrate structures in our diet and their impact on gut microbial diversity, which is crucial for overall health. It examines how the Western diet, characterized by high fat and low fiber, leads to a decrease in beneficial gut bacteria, potentially contributing to chronic diseases like type II diabetes and inflammatory bowel disease. By understanding how complex carbohydrates influence microbial communities, the research aims to identify dietary strategies that could restore gut health and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from chronic conditions such as type II diabetes, inflammatory bowel disease, or those interested in improving their gut health through dietary changes.
Not a fit: Patients with acute gastrointestinal infections or those not experiencing chronic health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that enhance gut health and reduce the risk of chronic diseases.
How similar studies have performed: Previous research has shown promising results in improving gut microbiota diversity through dietary interventions, indicating that this approach has potential for success.
Where this research is happening
West Lafayette, United States
- Purdue University — West Lafayette, United States (Active)
Researchers
- Principal investigator: Lindemann, Stephen Robert — Purdue University
- Study coordinator: Lindemann, Stephen Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.