How bacteria interact in the human body and colonize different areas.
Interactions underlying resilient bacterial communities and successful colonization of host niches
['FUNDING_OTHER'] · UNIV OF MASSACHUSETTS MED SCH WORCESTER · NIH-11088457
This study is looking at how different types of bacteria live in places like your gut and tumors, using specially modified bacteria to see how they work together, which could help us find better ways to treat infections and diseases related to bacteria.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MASSACHUSETTS MED SCH WORCESTER (nih funded) |
| Locations | 1 site (WORCESTER, UNITED STATES) |
| Trial ID | NIH-11088457 on ClinicalTrials.gov |
What this research studies
This research investigates how bacteria naturally inhabit various niches in the human body, such as the gut and tumors. By using genetically engineered bacteria, the study explores the interactions between different bacterial communities and how these interactions influence their ability to colonize host environments. The research employs a combination of functional genomics, computational analysis, and mathematical modeling to understand the complex dynamics of these bacterial communities over time. Patients may benefit from insights into bacterial behavior that could lead to improved treatments for infections and diseases associated with bacterial colonization.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with bacterial infections or conditions influenced by bacterial communities, such as those with gut disorders or certain cancers.
Not a fit: Patients who do not have bacterial infections or conditions related to bacterial colonization may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating bacterial infections and diseases linked to bacterial colonization.
How similar studies have performed: Other research has shown success in understanding bacterial interactions and their implications for health, indicating that this approach has potential for significant findings.
Where this research is happening
WORCESTER, UNITED STATES
- UNIV OF MASSACHUSETTS MED SCH WORCESTER — WORCESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MITCHELL, AMIR — UNIV OF MASSACHUSETTS MED SCH WORCESTER
- Study coordinator: MITCHELL, AMIR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: bacteria infection, bacterial disease, Bacterial Infections, Cancers