How air pollution and stress during pregnancy affect long-term obesity risks in mothers
Air Particulate Pollution and Stress: Effects and Mechanisms for Long-term Maternal Obesity Risks
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10880688
This study is looking at how air pollution and stress during pregnancy might affect mothers' long-term health and weight, and it’s for moms who want to understand how their environment could impact their well-being after having a baby.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10880688 on ClinicalTrials.gov |
What this research studies
This research investigates how exposure to air pollution and psychosocial stress during pregnancy may influence long-term weight gain and health in mothers. It focuses on the role of microRNAs released by the placenta, which may affect maternal tissues and contribute to obesity and cardiometabolic conditions. By examining the interactions between environmental factors and maternal health, the study aims to uncover critical mechanisms that could lead to better health outcomes for mothers. Participants may provide biological samples and health information to help understand these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women, particularly those experiencing high levels of stress or living in areas with significant air pollution.
Not a fit: Patients who are not pregnant or those who do not have concerns related to obesity or cardiometabolic health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing obesity and related health issues in mothers after pregnancy.
How similar studies have performed: While the specific joint effects of air pollution and stress on maternal health during pregnancy have not been extensively studied, related research has shown that environmental factors can significantly impact health outcomes.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COLICINO, ELENA — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: COLICINO, ELENA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease