How air pollution affects kidney health in agricultural workers
Particulate exposure and kidney health
This study is looking at how air pollution and working conditions, like heat and dehydration, might affect kidney health in sugarcane workers in Guatemala, so we can better understand the risks and help keep them safe.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11011482 on NIH RePORTER |
What this research studies
This research investigates the link between exposure to air contaminants and acute kidney injury among agricultural workers, particularly those in the sugarcane industry. It aims to understand how factors like heat stress and dehydration may worsen kidney health. By studying a population of sugarcane workers in Guatemala, the research will assess their exposure to harmful particles and identify personal risk factors that contribute to kidney dysfunction. The study will also explore the biological mechanisms behind these effects, focusing on a specific injury pathway related to vasopressin.
Who could benefit from this research
Good fit: Ideal candidates for this research are agricultural workers, particularly those involved in sugarcane production, who may be exposed to high levels of air contaminants.
Not a fit: Patients not working in agricultural settings or those without exposure to air pollution may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for kidney injury in agricultural workers exposed to harmful air pollutants.
How similar studies have performed: Previous research has indicated a connection between environmental pollutants and kidney health, suggesting that this study builds on established findings while exploring new mechanisms.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Adgate, John L. — University of Colorado Denver
- Study coordinator: Adgate, John L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.