How age and tumor location affect outcomes in children with brain tumors
Effects of age and lesion location on motor, behavioral and cognitive outcomes in pediatric posterior fossa tumors
This study is looking at how the age of children and where their brain tumors are located in the back part of the brain can affect their movement, behavior, and thinking skills, helping us understand how damage to this area might lead to challenges like autism or learning difficulties.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | American University NIH-funded |
| Lab location | 1 site (Washington, UNITED STATES) |
| Project ID | NIH-10438985 on NIH RePORTER |
What this research studies
This research investigates the impact of age and the specific location of brain tumors in the posterior fossa on motor, behavioral, and cognitive outcomes in children. It aims to understand how damage to the cerebellum, a brain region traditionally linked to motor control, also affects cognitive and behavioral functions. By analyzing data from pediatric patients, the study seeks to establish a connection between the location of brain lesions and the resulting developmental challenges, including risks for autism and cognitive impairments. The research employs advanced mapping techniques to correlate lesion locations with various outcomes, providing insights into how early cerebellar damage can influence long-term development.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with posterior fossa tumors, particularly those who have experienced cerebellar damage.
Not a fit: Patients with tumors located outside the posterior fossa or those who do not have cerebellar involvement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions for children affected by posterior fossa tumors, enhancing their developmental outcomes.
How similar studies have performed: Previous studies have shown success in linking lesion locations to outcomes in adult populations, but this approach is relatively novel in pediatric cases.
Where this research is happening
Washington, UNITED STATES
- American University — Washington, United States (Active)
Researchers
- Principal investigator: Malloy, Elizabeth Jane — American University
- Study coordinator: Malloy, Elizabeth Jane
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.