NIH-funded research R01 grant

How a simple, evidence-based approach helps mothers and kids in Peru feel better

Official title: Evaluating the effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of individual and intergenerational change

Funded at University of Notre Dame · NIH-11474425 · Data updated 2026-11-12

A study tests a flexible, lay-delivered mental-health program called CETA for mothers of young children in Lima to improve family well-being.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Notre Dame
NIH-funded
Lab location1 site (Notre Dame, United States)
Project startSeptember 12, 2025
Project endAugust 31, 2030
Funding year2026
Award (this year)$193,119
NIH project number3R01HD116815-02S1
Project IDNIH-11474425 on NIH RePORTER

Who could benefit from this research

Could help

Mothers of children aged 4–6 in Lima, Peru, living in low-resource communities and participating in an integrated community care setting.

Less likely to help

Families who do not respond to the intervention or who have conditions not addressed by CETA may see limited benefit.

What this research studies

This project will evaluate how well the Common Elements Treatment Approach works for mothers of 4–6 year-olds in an impoverished Lima district, using trained non-specialists to deliver care. It will look at direct effects on mothers and indirect effects on their children, families, and economic factors over time. The research will explore how delivery quality and neighborhood context influence outcomes, and it will measure sustainability and cost-effectiveness in a real-world community setting. By focusing on a Spanish-speaking population in a low-resource setting, the study aims to inform scalable approaches to child and family mental health. The results could guide future programs that extend evidence-based care to similar communities.

Why it matters

Potential benefit: If successful, families could experience better mental health, stronger child outcomes, and more cost-effective access to care.

How similar studies have gone: Prior studies show transdiagnostic, lay-delivered interventions can improve mental health in similar settings, with ongoing questions about long-term and indirect effects.

Where this research is happening

  • University of Notre Dame
    Notre Dame, United States
    Active

Researchers

  • Principal investigator: Miller-Graff, Laura E. — University of Notre Dame
  • Study coordinator: Miller-Graff, Laura E.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.