HOPE-inG: A cervical cancer screening plan for women with HIV in Ghana
Official title: The Impact of an Evidence-Based, Behavioral Cervical Cancer Screening Intervention among Women Living with HIV in Ghana (HOPE-inG): A Type 2 Hybrid Effectiveness Implementation Trial
Funded at Baylor University · NIH-11415518 · Data updated 2026-11-12
A study tests a home-based HPV self-sampling and a supportive communication approach to help women with HIV in Ghana screen for cervical cancer more often.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor University NIH-funded |
| Lab location | 1 site (Waco, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $231,354 |
| NIH project number | 5U01CA294757-03 |
| Project ID | NIH-11415518 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women living with HIV in Ghana who are eligible for cervical cancer screening and have access to participating health facilities.
✕Less likely to help
Women not living with HIV or not engaged with participating health facilities may not benefit from this program.
What this research studies
This project builds on a proven approach that combines HPV self-testing at home with a 3R communication model to encourage cervical cancer screening among women living with HIV in Ghana. It uses a Type 2 hybrid design to measure both how well the intervention works and how it can be implemented in real health settings. Four secondary-level facilities in Ghana will participate to see how to scale up adoption, uptake, and sustainment of screening. The study is led by Baylor University and collaborators, aiming to integrate CCS into routine care for WLWH.
Why it matters
Potential benefit: If successful, the HOPE intervention could dramatically increase cervical cancer screening rates among WLWH in Ghana, enabling earlier detection and better health outcomes.
How similar studies have gone: Earlier work showed HOPE doubled screening uptake in Ghana compared with routine care, suggesting potential for broader impact with scale-up.
Where this research is happening
-
Baylor University
Waco, United States Active
Researchers
- Principal investigator: Asare, Matthew — Baylor University
- Study coordinator: Asare, Matthew
Related research
Other NIH-funded projects on the same topics.
-
mSaada: a mobile tool to boost cervical cancer screening in western Kenya
A mobile app helps community health volunteers manage cervical cancer screening tasks and follow-up for women in low-resource areas.
-
HPV self-collection in HIV care to screen for cervical cancer in Ethiopia
A patient-centered program tests a simple HPV self-collection approach within HIV clinics in Ethiopia to help detect cervical cancer earlier.
-
HOPE-inG: Increasing cervical cancer screening for women with HIV in Ghana
A study tests a home-based HPV self-sampling approach plus a tailored communication plan to help women living with HIV in Ghana get screened more often for cervical cancer.
-
CODA-based cervical cancer screening for LMICs using CRISPR and fluorescence
A low-resource, rapid test called CODA uses CRISPR and light signals to detect cervical cancer markers in women in sub-Saharan Africa to improve screening.
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CODA-based cervical cancer screening in low-resource settings
A new, quick, low-cost test using CRISPR and fluorescence readouts to help screen for cervical cancer in women in sub-Saharan Africa.
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CATSystem: a digital tool to boost cervical cancer screening and follow-up in Kenya
A digital tracking system helps doctors and patients in Kenya improve cervical cancer screening, treatment referrals, and follow-up, especially for women living with HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.