NIH-funded research Sbir 2 grant

Home leg training device to improve knee osteoarthritis symptoms

Official title: Home-Based Leg Dexterity Trainer for Management of Knee Osteoarthritis

Funded at Neuromuscular Dynamics, LLC · NIH-11196710 · Data updated 2026-11-12

A home-based device program that trains leg stability to help adults with knee osteoarthritis reduce pain and improve function.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionNeuromuscular Dynamics, LLC
NIH-funded
Lab location1 site (La Crescenta, UNITED STATES)
Project startSeptember 25, 2024
Project endMay 31, 2027
Funding year2025
Award (this year)$714,138
NIH project number5R44AG090114-02
Project IDNIH-11196710 on NIH RePORTER

Who could benefit from this research

Could help

Adults with knee osteoarthritis, including those with prior ACL injury, who can sit for short exercise sessions and follow remote instructions are ideal candidates.

Less likely to help

People who need immediate knee surgery, have severe joint instability or deformity, or cannot perform the seated exercises are unlikely to benefit.

What this research studies

You would use a portable, wireless Leg Dexterity device while seated that challenges leg balance by compressing a springy platform. A tablet gives real-time feedback and uploads activity to a secure cloud so you and clinicians can track progress. The trial compares 8 weeks of this unstable-surface training (42 participants) with a dose-matched program of stable leg presses in a blinded design. Most training is done at home with remote monitoring and data collection.

Why it matters

Potential benefit: If successful, the device could lower knee pain and improve daily function without surgery.

How similar studies have gone: Other balance and sensorimotor training programs have shown benefits for knee pain and function, but this specific Leg Dexterity home device is novel and not yet widely tested.

Where this research is happening

  • Neuromuscular Dynamics, LLC
    La Crescenta, United States
    Active

Researchers

  • Principal investigator: Valero, Erika — Neuromuscular Dynamics, LLC
  • Study coordinator: Valero, Erika

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.