NIH-funded research Sbir 2 grant

Home-based Leg Dexterity Training for knee osteoarthritis

Official title: Home-Based Leg Dexterity Trainer for Management of Knee Osteoarthritis

Funded at Neuromuscular Dynamics, LLC · NIH-11390950 · Data updated 2026-11-12

A portable, wireless device helps adults with ACL injury or knee osteoarthritis practice quick, instability-based leg movements at home to ease pain and improve function.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionNeuromuscular Dynamics, LLC
NIH-funded
Lab location1 site (La Crescenta, UNITED STATES)
Project startSeptember 25, 2024
Project endMay 31, 2027
Funding year2026
Award (this year)$682,217
NIH project number5R44AG090114-03
Project IDNIH-11390950 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older with ACL injury or knee OA who can use a home device and access the cloud-enabled system.

Less likely to help

Individuals without access to home internet or who cannot safely perform the device-based exercises may not benefit.

What this research studies

This grant supports testing a home-based Leg Dexerity System that uses a small, unstable platform to train knee and leg muscles through short, rapid sensorimotor tasks. Participants will perform eight weeks of guided exercises at home, with a tablet providing feedback and data uploaded securely to a clinician-visible cloud. The study compares this training to stable leg presses in a blinded, dose-matched design to see if the unstable training reduces pain and improves function in non-surgical knee care. If successful, the project will help bring a clinically validated, patient-friendly option for managing knee OA and ACL-related issues outside the clinic.

Why it matters

Potential benefit: If successful, patients could use this home device to reduce knee pain and improve function without surgery.

How similar studies have gone: Previous work on home-based sensorimotor training has shown promise in improving knee function, but this specific unstable-foot–ground training is a novel approach needing validation.

Where this research is happening

  • Neuromuscular Dynamics, LLC
    La Crescenta, United States
    Active

Researchers

  • Principal investigator: Valero, Erika — Neuromuscular Dynamics, LLC
  • Study coordinator: Valero, Erika

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.