HIV research network across the Americas improving care, outcomes, and prevention
Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)
Funded at Vanderbilt University Medical Center · NIH-11541270 · Data updated 2026-11-12
A large international network collaborates to understand and improve HIV care and health outcomes in the Americas, using large databases and partnerships with clinics.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | June 15, 2006 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $93,006 |
| NIH project number | 3U01AI069923-22S7 |
| Project ID | NIH-11541270 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV across participating sites in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States, including pregnant women and adolescents.
✕Less likely to help
Patients outside the participating countries or those not receiving care at CCASAnet/leDEA sites may not directly benefit.
What this research studies
This grant supports a long-standing collaborative network that collects and harmonizes HIV care data from multiple countries in the Americas. It uses advanced statistics and informatics to analyze treatment outcomes, adherence, and the continuum of care, and to mentor researchers at partner sites. The work includes studying missed follow-up, outcomes for pregnant women, and co-existing conditions like substance use and mental health, with prospective studies embedded in clinical settings. The goal is to generate insights that can improve patient care, inform policies, and build local research capacity.
Why it matters
Potential benefit: Improved understanding of how to keep people with HIV engaged in care and optimize treatments across diverse populations.
How similar studies have gone: Previous network analyses have successfully informed clinical guidelines and improved understanding of treatment outcomes in HIV care.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
- Study coordinator: Castilho, Jessica L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.