NIH-funded research U01 cooperative agreement

HIV Care and Outcomes Across the Americas Network

Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)

Funded at Vanderbilt University Medical Center · NIH-11541271 · Data updated 2026-11-12

A long-running network of doctors and researchers across the Americas examines how people living with HIV are cared for, how outcomes differ, and what could improve treatment and health in real-world settings.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startJune 15, 2006
Project endMay 31, 2028
Funding year2026
Award (this year)$255,568
NIH project number3U01AI069923-22S8
Project IDNIH-11541271 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV who receive care at participating sites in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States.

Less likely to help

Patients outside the study regions or not linked to participating HIV care sites may not directly benefit.

What this research studies

This project uses data from HIV clinics in many countries to understand how people with HIV are doing over time, including care gaps and outcomes. It harmonizes and analyzes complex health records to identify factors that influence treatment success and where improvements are possible. The effort also strengthens local researchers’ skills and leadership through mentoring and education, aiming to broaden the impact of findings across the region.

Why it matters

Potential benefit: If successful, the work could improve HIV care strategies, reduce treatment gaps, and inform policies across the Americas.

How similar studies have gone: Previous multicountry HIV research networks have improved understanding of care continua and treatment outcomes, with ongoing enhancements in biostatistics and informatics.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
  • Study coordinator: Castilho, Jessica L

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.