NIH-funded research U01 cooperative agreement

HIV care and outcomes across the Americas network

Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)

Funded at Vanderbilt University Medical Center · NIH-11541268 · Data updated 2026-11-12

A network-led effort across several countries to improve understanding and care of people living with HIV through shared data, mentorship, and collaborative studies.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startJune 15, 2006
Project endMay 31, 2028
Funding year2026
Award (this year)$86,884
NIH project number3U01AI069923-22S5
Project IDNIH-11541268 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV across Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States who receive care at participating sites.

Less likely to help

Patients not engaged with HIV care or outside participating sites may not directly benefit.

What this research studies

This grant supports CCASAnet, a collaboration of HIV clinical care sites and researchers across the Americas that harmonizes data and builds biostatistics and informatics methods. It aims to map the HIV care continuum, understand who remains lost to follow-up, and study outcomes in pregnancy, non-communicable diseases, tuberculosis co-infection, substance use, and mental health. The work includes data coordination, methodological development, and educational mentoring to grow research leadership at participating sites. The project uses observational data from multiple clinics to inform better treatment practices and policies.

Why it matters

Potential benefit: Improved understanding of HIV care and outcomes could lead to better treatment strategies and health outcomes for people living with HIV in the Americas.

How similar studies have gone: Past collaborations within leDEA have produced valuable observational insights and informed care practices; this network builds on those successes with expanded scope.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
  • Study coordinator: Castilho, Jessica L

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.