HIV care and outcomes across the Americas network
Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)
Funded at Vanderbilt University Medical Center · NIH-11541265 · Data updated 2026-11-12
A regional network is studying how people living with HIV are doing across many countries in the Americas to improve care and outcomes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | June 15, 2006 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $224,528 |
| NIH project number | 3U01AI069923-22S2 |
| Project ID | NIH-11541265 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV receiving care at participating sites in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States, including pregnant women, adolescents, and older adults.
✕Less likely to help
Some individuals may not directly benefit if they are not engaged with care at participating sites or if findings do not immediately translate to changes in their local care.
What this research studies
This grant supports a long-standing international collaboration that collects and analyzes HIV patient data from sites in several Americas countries. The team harmonizes diverse databases, develops new statistical and informatics methods, and provides training to enhance local research capacity. The goal is to understand the HIV care continuum, identify people lost to follow-up, and explore how AIDS-related health issues and treatments play out in real-world settings. The work includes prospective studies embedded in routine care to examine outcomes such as treatment success, non-communicable disease risk, mental health, and substance use among diverse populations.
Why it matters
Potential benefit: If successful, patients could benefit from improved HIV care strategies, better retention in care, and insights that reduce morbidity and mortality related to HIV and coexisting conditions.
How similar studies have gone: Previous international HIV cohorts like leDEA have produced actionable insights and improved understanding of HIV care in real-world settings.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
- Study coordinator: Castilho, Jessica L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.