NIH-funded research U01 cooperative agreement

HIV care and outcomes across the Americas network

Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)

Funded at Vanderbilt University Medical Center · NIH-11541262 · Data updated 2026-11-12

A patient-focused program to better understand how HIV care is delivered and what helps people stay healthy across the Americas.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startJune 15, 2006
Project endMay 31, 2028
Funding year2026
Award (this year)$117,131
NIH project number3U01AI069923-22S1
Project IDNIH-11541262 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV who receive care at participating CCASAnet sites in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States, including special groups like pregnant women and adolescents.

Less likely to help

Patients receiving care outside the CCASAnet network or those not contributing data may not directly benefit from these findings.

What this research studies

CCASAnet brings together HIV clinics and researchers from several countries to study real-world care and outcomes. It harmonizes patient data and builds new methods to analyze how people with HIV are doing over time. The project also focuses on improving education and mentoring for clinical research teams, including junior researchers. In the next cycle, the network will look at care gaps, pregnancy-related care, the intersection of HIV with non-communicable diseases, and health issues like substance use and mental health.

Why it matters

Potential benefit: If successful, this work could lead to better care pathways and improved health outcomes for people living with HIV across the region.

How similar studies have gone: Previous international observational networks have successfully used harmonized data to inform guidelines and improve care.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
  • Study coordinator: Castilho, Jessica L

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.