High‑intensity exercise program to help adults with high anxiety sensitivity quit smoking

Efficacy and implementation of exercise-based smoking cessation treatment for adults with high anxiety sensitivity

['FUNDING_R01'] · UNIVERSITY OF TEXAS AT AUSTIN · NIH-11115867

This project uses a supervised high‑intensity exercise program to help adult smokers who are especially sensitive to anxiety symptoms quit smoking and reduce withdrawal and craving.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS AT AUSTIN (nih funded)
Locations1 site (AUSTIN, UNITED STATES)
Trial IDNIH-11115867 on ClinicalTrials.gov

What this research studies

You would join a program for adult smokers who have high anxiety sensitivity that pairs a 15‑week high‑intensity exercise regimen with smoking‑cessation support. The team will enroll adults, deliver on‑site exercise sessions, and track smoking status, anxiety sensitivity, withdrawal, craving, and mood over time. Researchers will also study how the program can be delivered in real‑world settings so clinics or community centers could offer it. The goal is to see if exercise both helps people stop smoking and can be implemented broadly.

Who could benefit from this research

Good fit: Ideal candidates are adult smokers (21 years or older) who report high anxiety sensitivity and are willing and able to participate in a 15‑week high‑intensity exercise program while trying to quit.

Not a fit: People who do not smoke, have low anxiety sensitivity, or who cannot safely perform high‑intensity exercise due to medical limitations are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, the program could help smokers with high anxiety sensitivity quit more often and reduce anxiety, withdrawal, and cravings.

How similar studies have performed: Earlier phase I/II work by the team showed promising results that high‑intensity exercise can lower anxiety sensitivity and nicotine withdrawal, but this larger implementation effort will test effectiveness and delivery more broadly.

Where this research is happening

AUSTIN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Anxiety Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.