Helping young women stay on hormone therapy after breast cancer
Active Symptom Monitoring and Endocrine Therapy Persistence in Young Women with Breast Cancer
This project asks premenopausal women with hormone receptor–positive breast cancer to report symptoms regularly online to help them remain on endocrine therapy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11251815 on NIH RePORTER |
What this research studies
You would be asked to use a web-based tool to report symptoms between clinic visits so providers can spot side effects early. The team will follow a diverse group of premenopausal women taking endocrine therapy with ovarian suppression and track who stops treatment early. Researchers will look for which symptoms and patient factors predict benefit from this active symptom monitoring approach. The goal is to improve communication, reduce bothersome toxicities, and support staying on therapy.
Who could benefit from this research
Good fit: Ideal candidates are premenopausal women with hormone receptor–positive breast cancer who are prescribed endocrine therapy, often with ovarian function suppression.
Not a fit: Men, postmenopausal women, people with non–hormone receptor breast cancers, or those not taking endocrine therapy (or without access to the web-based tool) are unlikely to benefit from this project.
Why it matters
Potential benefit: If successful, this approach could improve symptom control and help more women stay on life‑saving endocrine therapy, lowering the chance of cancer recurrence.
How similar studies have performed: Active symptom monitoring has improved quality of life and survival in advanced cancer, but its use to keep early-stage patients on endocrine therapy is relatively new and less tested.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Henry, Norah Lynn — University of Michigan at Ann Arbor
- Study coordinator: Henry, Norah Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.