Helping people with HIV in Zambia return to and stay in care

Sequential Strategies to Reach and Reengage Individuals after Lapses from HIV Care in Zambia

NIH-funded research Washington University · NIH-11386473

This project combines personalized outreach by navigators with community medication delivery to help people with HIV in Zambia who have stopped treatment get back on antiretroviral therapy and remain engaged in care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11386473 on NIH RePORTER

What this research studies

If you've missed HIV care, the team will try to reach you with a trained navigator who tailors outreach, coordinates services, and offers psychosocial support. After you return, the study offers community-based medication delivery to make it easier to get your ART without repeated clinic visits. The project will test different ways and timings to combine these approaches so they work better over the long term. Your viral load and care visits will be followed to see whether these supports keep people on treatment.

Who could benefit from this research

Good fit: People living with HIV in Zambia who have missed clinic visits or stopped taking antiretroviral therapy and could be reached through participating clinics are the ideal candidates.

Not a fit: People who are already continuously engaged in HIV care and stable on ART, or those living outside the study catchment areas, are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, this approach could increase timely return to treatment, reduce repeat lapses, and lower the chance of high viral load and related illness.

How similar studies have performed: Previous work shows navigation and community medication delivery can help people newly starting or stable on ART, but combining these approaches specifically after treatment lapses is relatively untested.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusChronic Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.