Heart Failure CardioScore: an AI tool to help ED doctors diagnose and predict outcomes for heart failure
Official title: Derivation and Validation of the Heart Failure CardioScore: an AI Diagnostic for HeartFailure using Novel Biomarkers and Clinical Data
Funded at Prenosis, INC. · NIH-11315860 · Data updated 2026-11-12
A new AI-based tool uses biomarkers and patient data to help doctors diagnose acute heart failure more accurately in the emergency department.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Prenosis, INC. NIH-funded |
| Lab location | 1 site (Champaign, United States) |
| Project start | September 1, 2026 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,218,102 |
| NIH project number | 1R44HL180159-01A1 |
| Project ID | NIH-11315860 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older who present to the emergency department with suspected acute heart failure or related symptoms.
✕Less likely to help
Patients without suspected acute heart failure or those not represented in the study data may not benefit.
What this research studies
This project aims to create the Heart Failure CardioScore, an AI system that blends new biomarkers with clinical information to support ED clinicians in diagnosing acute heart failure. By improving diagnostic precision, it could reduce unnecessary admissions and guide better patient management. The study will develop and validate the AI model using real-world data and biomarkers, with a focus on timely, actionable results for clinicians and patients.
Why it matters
Potential benefit: If successful, patients with suspected acute heart failure could receive faster, more accurate diagnoses and more appropriate treatment decisions.
How similar studies have gone: Other studies using AI with biomarkers have shown promise in improving diagnostic accuracy, but this project advances with novel biomarkers and integrated clinical data.
Where this research is happening
-
Prenosis, INC.
Champaign, United States Active
Researchers
- Principal investigator: Reddy, Bobby — Prenosis, INC.
- Study coordinator: Reddy, Bobby
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.