Health system depression treatment and outcomes in diverse communities
Official title: Health System Depression Treatment and Outcomes
Funded at Kaiser Foundation Research Institute · NIH-11419827 · Data updated 2026-11-12
This project studies how Black, Hispanic, and Asian patients with depression are treated in real-world health systems and what factors influence whether they receive care and how well it works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | September 19, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $2,727,025 |
| NIH project number | 4R01MD020056-02 |
| Project ID | NIH-11419827 on NIH RePORTER |
Who could benefit from this research
✓Could help
People from Black, Hispanic, and Asian communities with depression who receive or need treatment within the participating health systems.
✕Less likely to help
Patients not receiving care or not influencing treatment decisions may see no direct benefit.
What this research studies
The grant looks at real-world data from multiple health systems to understand why some patients don’t get depression treatment and whether partial treatment can be as helpful as full treatment. It uses a health-systems framework to identify determinants of disparities and to connect findings to practice improvements. The study analyzes large groups of Black, Hispanic, Asian, and White patients to compare treatment patterns and outcomes. The goal is to inform more equitable depression care across diverse communities.
Why it matters
Potential benefit: If successful, the work could guide health systems to close treatment gaps and improve depression outcomes for minority communities.
How similar studies have gone: Prior work shows disparities in treatment, but this project adds real-world, system-level analysis and implementation focus.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Coleman, Karen Jacqueline — Kaiser Foundation Research Institute
- Study coordinator: Coleman, Karen Jacqueline
Related research
Other NIH-funded projects on the same topics.
-
Biotype-based Personalization of Antidepressant Augmentation in Late-Life Depression
A multi-site study will test a computer-guided approach to choosing the best augmentation option for older adults with treatment-resistant depression.
-
Suubi-Mhealth: a mobile app to help Ugandan youth with HIV manage depression and ART adherence
A mobile app designed for 14–17 year olds in Uganda aims to support mental health and keep HIV treatment on track.
-
Group-based postpartum depression prevention: in-person vs. virtual delivery
A large study is testing whether the ROSE group program delivered virtually to pregnant people is just as helpful as the in-person version in preventing postpartum depression.
-
DESCANSO: A friendly CBT plan to ease depression, sleep problems, and fatigue in Latino cancer patients
A Spanish-speaking CBT program called DESCANSO is being tested to help Latino cancer patients feel less tired, sleep better, and happier.
-
Personalized iTBS for Depression: Faster, Targeted Brain Stimulation
A personalized, time-efficient brain stimulation approach may help people with treatment-resistant depression achieve better relief using tailored iTBS settings.
-
Ultrasound-guided brain circuit targets for treatment-resistant depression
This grant tests whether focused ultrasound can safely and reversibly adjust brain circuits linked to negative mood in people with treatment-resistant depression.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.