NIH-funded research NIH-funded research

Genomics Core for Appalachian Health Research (SMART Core)

Official title: SMART Core

Funded at Marshall University · NIH-11416383 · Data updated 2026-11-12

A genomic research core provides sequencing, data analysis, and training to study diseases and health problems in the Appalachian region.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMarshall University
NIH-funded
Lab location1 site (Huntington, UNITED STATES)
Project startSeptember 30, 2001
Project endJuly 31, 2029
Funding year2026
Award (this year)$114,676
NIH project number5P20GM103434-26
Project IDNIH-11416383 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are researchers and clinicians within the WV-INBRE network and Appalachian-region communities who are applying genomic methods to study candidate disease genes and related health conditions.

Less likely to help

Patients would not directly access the core services, which are used by researchers; benefits accrue through downstream research.

What this research studies

This core-based grant supports access to high-throughput sequencing, data analysis, and genomic tools for researchers at Marshall University and the WV-INBRE network. It will offer services like whole-genome, exome, RNA sequencing, microbiome, and chromatin studies, plus single-cell and spatial transcriptomics in the near future. The program includes design guidance, software access, RNA/DNA quality checks, and hands-on training to help investigators generate meaningful genomics data. Researchers, including undergraduates, can use these resources to push forward projects related to candidate disease genes and regional health challenges.

Why it matters

Potential benefit: If successful, patients in the Appalachian region could benefit from faster discovery of disease genes and more precise genomic analyses guiding future diagnostics and therapies.

How similar studies have gone: Similar core facilities have accelerated genomic research by providing centralized sequencing and analysis, though benefits depend on project quality and collaboration.

Where this research is happening

  • Marshall University
    Huntington, United States
    Active

Researchers

  • Principal investigator: Salisbury, Travis — Marshall University
  • Study coordinator: Salisbury, Travis

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.