Genomics and biology of psychiatric disorders to improve care
Official title: Psychiatric Genomics Consortium: Mechanisms and Translation
Funded at Univ of North Carolina Chapel Hill · NIH-11566448 · Data updated 2026-11-12
A large research effort will combine genetic data from many people to better understand why bipolar disorder and related conditions develop, with the goal of making future treatments and care more precise.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 1, 2026 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $169,357 |
| NIH project number | 3R01MH142618-01S4 |
| Project ID | NIH-11566448 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with bipolar disorder or related psychiatric conditions, and their families, may benefit from future advances in genetics-informed care and risk assessment.
✕Less likely to help
People without bipolar disorder or related conditions may not directly benefit from this research, though broader genomic insights could still emerge.
What this research studies
This project will integrate genetic and functional genomic data from diverse populations to map how genetic differences influence psychiatric illness. By identifying variants linked to serious disorders and tracing how they affect biology, the team aims to clarify disease mechanisms and where interventions could help. The work will also examine how different psychiatric and medical conditions share genetic influences, and will map when and where these genetic effects act in the body. Training and outreach are emphasized to translate discoveries into clinical relevance for patients and clinicians.
Why it matters
Potential benefit: If successful, findings could lead to more targeted strategies for diagnosis, risk prediction, and personalized treatment in bipolar disorder and related conditions.
How similar studies have gone: Previous large genomic collaborations have yielded meaningful insights into psychiatric risk and biology, supporting the potential for impactful findings here.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Sullivan, Patrick F — Univ of North Carolina Chapel Hill
- Study coordinator: Sullivan, Patrick F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.