Genetics-driven understanding and translation of bipolar disorder
Official title: Psychiatric Genomics Consortium: Mechanisms and Translation
Funded at Univ of North Carolina Chapel Hill · NIH-11566443 · Data updated 2026-11-12
A big genetics project aims to uncover how inherited factors contribute to bipolar disorder and how that knowledge could be turned into better care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 1, 2026 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $119,122 |
| NIH project number | 3R01MH142618-01S2 |
| Project ID | NIH-11566443 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with bipolar disorder or related psychiatric conditions who are willing to participate in genetic data sharing or related analyses if applicable.
✕Less likely to help
People not represented in genetic datasets or whose data cannot be shared may not directly benefit.
What this research studies
This grant brings together researchers to analyze large genetic data sets to find variants linked to bipolar disorder and related conditions. It will also look at how different genetic influences shape risk and symptoms, and how to connect discoveries to real-world biology. By mapping genetic signals to biological contexts and functional data, the project aims to reveal mechanisms behind illness and potential paths to clinical use. The work builds on many years of collaboration and uses advanced methods to integrate diverse data sources.
Why it matters
Potential benefit: Understanding genetic drivers could lead to new biomarkers and targeted approaches to treatment and prevention.
How similar studies have gone: Previous large-scale psychiatric genetics efforts have successfully identified genetic influences and informed biological understanding, supporting optimism for this approach.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Sullivan, Patrick F — Univ of North Carolina Chapel Hill
- Study coordinator: Sullivan, Patrick F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.