NIH-funded research NIH-funded research

Genetic and brain-related roots of dad’s care behaviors

Official title: Genetic and neural mechanisms of paternal care behavior

Funded at University of Chicago · NIH-11537949 · Data updated 2026-11-12

Researchers will study how genes and brain processes influence paternal care in small freshwater fish to understand why some dads help raise offspring.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startJuly 9, 2024
Project endApril 30, 2029
Funding year2026
Award (this year)$403,462
NIH project number7R35GM154624-03
Project IDNIH-11537949 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to patients; research involves animal models (fish) to understand behavior.

Less likely to help

Direct patient benefit is unlikely since the work is in fish models, not humans.

What this research studies

This project looks at how genetics and brain function shape paternal care in darter fishes, using modern genetic and neurobiological methods. Researchers will compare different species and lineages to identify genetic variants and neural pathways linked to caring behavior. The study combines natural populations with controlled analyses to map genes to specific behaviors and neural activity. Findings could reveal fundamental mechanisms that drive paternal care across species, including humans, by connecting genes to behavior through brain biology.

Why it matters

Potential benefit: Could enhance understanding of the biological roots of parental care, which may inform treatments for social or developmental disorders in the long term.

How similar studies have gone: Prior work shows genetic and neural bases for behavior in animals; this project extends that to paternal care across darter species.

Where this research is happening

  • University of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Moran, Rachel L — University of Chicago
  • Study coordinator: Moran, Rachel L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.