NIH-funded research R01 grant

Gastric rhythm map to understand stomach problems using a new noninvasive tool

Official title: Definitive Evaluation of Gastric Dysrhythmia as a Disease Mechanism by a Novel Body Surface Gastric Mapping Technique

Funded at University of Louisville · NIH-11611507 · Data updated 2026-11-12

A new noninvasive body surface mapping method is being tested to see if abnormal stomach electrical rhythms explain chronic stomach problems like functional dyspepsia and persistent nausea.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Louisville
NIH-funded
Lab location1 site (Louisville, United States)
Project startJuly 15, 2024
Project endApril 30, 2028
Funding year2026
Award (this year)$108,000
NIH project number3R01DK137790-03S1
Project IDNIH-11611507 on NIH RePORTER

Who could benefit from this research

Could help

Adults with functional dyspepsia or chronic nausea and vomiting syndromes who are undergoing evaluation with the BSGM approach.

Less likely to help

Patients without gastric symptoms or who cannot participate in noninvasive mapping may not benefit.

What this research studies

This project will use Body Surface Gastric Mapping (BSGM), a painless test, to map the stomach’s electrical activity in adults with functional dyspepsia and related symptoms. By comparing BSGM patterns with patients’ symptoms, researchers hope to identify clear biomarkers that define different forms of gastric dysfunction. The study builds on prior lab work and will analyze data from large clinical studies to determine if dysrhythmias are a key mechanism. If successful, this could lead to better diagnostics and more targeted therapies in the future.

Why it matters

Potential benefit: If successful, patients could receive more accurate diagnoses and personalized treatments for chronic stomach symptoms.

How similar studies have gone: Prior work with BSGM has shown promising biomarkers and spatial patterns not detectable by older methods.

Where this research is happening

  • University of Louisville
    Louisville, United States
    Active

Researchers

  • Principal investigator: Abell, Thomas Lyman — University of Louisville
  • Study coordinator: Abell, Thomas Lyman

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.