Gadolinium Safety and Skin and Organ Effects from MRI Contrast
Official title: Gadolinium Safety: Dermatologic Consequences of Magnetic Resonance Imaging Contrast Agents and Permanent Metal Retention
Funded at Albuquerque VA Medical Center · NIH-11188905 · Data updated 2026-11-12
This grant investigates how gadolinium from MRI contrast could affect skin and other tissues, aiming to understand toxic effects and protect patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albuquerque VA Medical Center NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project start | April 1, 2026 |
| Project end | March 31, 2030 |
| Funding year | 2026 |
| NIH project number | 1I01BX006187-01A2 |
| Project ID | NIH-11188905 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who have had gadolinium-enhanced MRI and demonstrate related symptoms or at-risk conditions.
✕Less likely to help
Individuals with no exposure to gadolinium or no related symptoms are less likely to benefit.
What this research studies
From a patient lens, this project looks at how gadolinium, a substance used in many MRIs, may stay in the body and cause long-term skin and tissue problems. Researchers will study cellular and molecular changes to identify why some people develop fibrotic or damage-related conditions after exposure. The work builds on prior findings and uses laboratory and translational approaches to map pathways and potential targets for therapy. The goal is to develop safer imaging practices and treatments for those who experience complications after gadolinium exposure.
Why it matters
Potential benefit: If successful, the work could lead to safer MRI practices and new therapies for gadol dysregulated tissue and fibrosis.
How similar studies have gone: Previous studies have linked gadolinium exposure to fibrotic and inflammatory responses, but detailed mechanisms are still being explored.
Where this research is happening
-
Albuquerque VA Medical Center
Albuquerque, United States Active
Researchers
- Principal investigator: Wagner, Brent — Albuquerque VA Medical Center
- Study coordinator: Wagner, Brent
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.