NIH-funded research R21 grant

Fullwave physics-guided ultrasound modeling for faster, clearer imaging

Official title: Fullwave Physics-Informed Neural Networks for Rapid Ultrasound Simulation, Quantitative Imaging, and Adaptive Focusing

Funded at University of Texas Dallas · NIH-11442457 · Data updated 2026-11-12

A patient-friendly project to make ultrasound images more accurate and reliable by using advanced computer models that simulate how ultrasound waves move through body tissues.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Dallas
NIH-funded
Lab location1 site (Richardson, United States)
Project startAugust 7, 2026
Project endJune 30, 2029
Funding year2026
Award (this year)$186,674
NIH project number1R21EB039965-01
Project IDNIH-11442457 on NIH RePORTER

Who could benefit from this research

Could help

Patients with conditions where ultrasound is used for abdominal or tissue characterization, such as liver disease or other abdominal pathologies, may benefit from improved imaging.

Less likely to help

Some patients with imaging scenarios where ultrasound is already optimal or where changing imaging methods provides no added value may see no benefit.

What this research studies

This grant focuses on creating a fast, physics-informed neural network approach to ultrasound that can predict how sound travels through fat, muscle, and bone. By embedding realistic wave equations into an interpretable model, the team aims to produce faster simulations and more precise tissue property maps. The goal is to improve image quality and quantitative measurements in ultrasound, potentially aiding diagnosis and treatment planning. The work involves collaboration between computer science and medical imaging experts at the University of Texas at Dallas, with results that could translate into better bedside ultrasound tools.

Why it matters

Potential benefit: If successful, this could lead to faster, more accurate ultrasound imaging and quantitative tissue maps that help clinicians diagnose diseases more reliably.

How similar studies have gone: Previous work has shown promise for physics-informed models in imaging, but clinical adoption remains limited, making this approach novel and potentially impactful.

Where this research is happening

  • University of Texas Dallas
    Richardson, United States
    Active

Researchers

  • Principal investigator: Li, You — University of Texas Dallas
  • Study coordinator: Li, You

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.