Finding ways to reduce inflammation and muscle loss in cancer patients
Control of cancer cachexia via stimulation of resolution of inflammation
This study is looking at ways to help cancer patients who are losing muscle and feeling weak due to inflammation, by exploring how certain molecules can help clear out damaged cells and support muscle recovery, with the goal of finding better treatments to improve their well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11004394 on NIH RePORTER |
What this research studies
This research investigates cancer cachexia, a serious condition that causes muscle wasting and inflammation in cancer patients. The team aims to understand how inflammation can be resolved in the body, using specialized molecules that help clear cellular debris and promote muscle regeneration. By studying these processes, they hope to develop new treatments that can counteract the harmful effects of inflammation and improve the quality of life for patients suffering from cachexia. The research will utilize established experimental systems to explore these mechanisms in detail.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are experiencing cachexia and related symptoms.
Not a fit: Patients who do not have cancer or those who are not experiencing cachexia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that alleviate muscle loss and improve overall health in cancer patients experiencing cachexia.
How similar studies have performed: While the approach of stimulating the resolution of inflammation is relatively novel, there is emerging evidence suggesting that similar strategies may have potential in other inflammatory conditions.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Panigrahy, Dipak — Beth Israel Deaconess Medical Center
- Study coordinator: Panigrahy, Dipak
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.