Finding types of type 2 diabetes using blood metabolites and genes in diverse adults
Metabolomic and genomic expansion of type 2 diabetes subtyping in multiethnic populations
Combining blood metabolite and genetic information to find different kinds of type 2 diabetes in adults from multiple ethnic groups.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-11172652 on NIH RePORTER |
What this research studies
You would be contributing samples and health data to a project that combines blood metabolite profiling (metabolomics) and genetic information to identify distinct subtypes of type 2 diabetes. The research team will analyze data from large U.S. cohort studies that include African American, Hispanic/Latino, Asian, and other adults to capture differences across racial/ethnic groups and ages. By integrating metabolites, genomes, and clinical measures, they aim to link biological drivers to risk of complications and likely treatment responses. The goal is to make diabetes care more personalized based on a person's biology.
Who could benefit from this research
Good fit: Adults (age 21+) living with type 2 diabetes—especially African American, Hispanic/Latino, Asian, or other underrepresented groups—are the primary candidates for this work.
Not a fit: People without type 2 diabetes, children under 21, or those not represented in the included cohorts are unlikely to get direct benefit from this project.
Why it matters
Potential benefit: If successful, this work could help doctors tailor treatments and better predict complications for people with type 2 diabetes.
How similar studies have performed: Prior research on diabetes subtypes has shown promise in linking clinical and genetic patterns to outcomes, but most earlier work lacked the racial and age diversity emphasized here.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Bancks, Michael Patrick — Wake Forest University Health Sciences
- Study coordinator: Bancks, Michael Patrick
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.