Finding the best ways to prevent heart disease in cancer survivors
Official title: Modeling Best Approaches for Cardiovascular Disease Prevention in Cancer Survivors
Funded at Icahn School of Medicine at Mount Sinai · NIH-10995346 · Data updated 2026-11-12
This study is looking for the best ways to help cancer survivors—especially those who had breast, prostate, or lung cancer—stay heart-healthy by understanding how their cancer treatments and other health factors work together.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $697,894 |
| NIH project number | 5R01CA271604-03 |
| Project ID | NIH-10995346 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have survived breast, prostate, or lung cancer and are at risk for cardiovascular disease.
✕Less likely to help
Patients who are currently undergoing active cancer treatment or have other unrelated severe health conditions may not benefit from this research.
What this research studies
This research aims to identify effective strategies for preventing cardiovascular disease (CVD) among survivors of breast, prostate, and lung cancer. It focuses on understanding how traditional CVD risk factors and cancer treatments interact to affect heart health. By analyzing data from over 6 million cancer survivors, the study will explore tailored prevention methods that consider both cancer-related risks and the unique health challenges faced by these patients. The goal is to improve overall health outcomes and quality of life for cancer survivors.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of heart disease in cancer survivors, improving their long-term health and survival rates.
How similar studies have gone: Previous research has shown promising results in using tailored prevention strategies for cardiovascular disease in other high-risk populations, suggesting potential success for this approach in cancer survivors.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Wisnivesky, Juan P — Icahn School of Medicine at Mount Sinai
- Study coordinator: Wisnivesky, Juan P
Related research
Other NIH-funded projects on the same topics.
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Aging, DNA Methylation, and Cardio Risk in Breast Cancer Survivors
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-
Best ways to prevent heart disease in breast, prostate, and lung cancer survivors
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-
Personalized heart risk prediction for childhood cancer survivors
This project helps predict and lower the chance of heart disease for people who survived cancer as children.
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Understanding Heart Risks for Childhood Cancer Survivors
This work aims to create better tools to understand and prevent heart problems in people who had cancer as children.
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A program to help cancer survivors increase physical activity and reduce heart disease risk
This study is testing a new program called ActivityChoice that helps cancer survivors find and join physical activity options to lower their chances of heart disease, making it easier for them to choose what works best for them.
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Understanding how genetic changes in blood cells relate to heart disease in people with HIV
A study will look at how age-related blood cell mutations and large chromosomal changes might contribute to heart disease risk in people living with HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.