Finding new ways to treat persistent bladder pain

Spinal targets to treat persistent bladder pain

NIH-funded research VA Medical Center - Lexington, Ky · NIH-10923182

This study is looking for new ways to help veterans and others who suffer from painful bladder conditions by exploring how certain parts of the spinal cord can help reduce their pain.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Medical Center - Lexington, Ky NIH-funded
Lab location1 site (Lexington, United States)
Project IDNIH-10923182 on NIH RePORTER

What this research studies

This research focuses on interstitial cystitis/bladder pain syndrome (IC/BPS), a painful condition that significantly impacts the quality of life for many individuals, particularly veterans. The study aims to identify new spinal targets that can help modulate persistent bladder pain using a rodent model that mimics the human condition. By investigating specific receptors and proteins in the spinal cord, the researchers hope to uncover novel therapeutic approaches that do not rely on traditional treatments. The ultimate goal is to improve pain management for patients suffering from this debilitating syndrome.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from interstitial cystitis or bladder pain syndrome, particularly veterans.

Not a fit: Patients with bladder pain resulting from identifiable infections or injuries may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that significantly alleviate persistent bladder pain for affected patients.

How similar studies have performed: While the approach of targeting spinal mechanisms for bladder pain is innovative, similar studies have shown promise in other pain management contexts.

Where this research is happening

Lexington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions bladder infectionBladder Injurybladder pain syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.