Finding New Medicines for Drug-Resistant Bacterial Infections
Expanding the small molecule toolbox through novel applications of fluorinated alkenes
This research aims to discover new chemical tools and strategies to create effective treatments against bacterial infections that no longer respond to current antibiotics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tennessee Health Sci Ctr NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-11190970 on NIH RePORTER |
What this research studies
Many bacterial infections are becoming increasingly difficult to treat because they have developed resistance to existing antibiotics. Our team is dedicated to finding entirely new types of small molecules that can successfully fight these resistant bacteria. We are exploring the unique chemical properties of compounds called fluorinated alkenes to build these novel molecules. This approach helps us design better ways to target essential parts of bacterial cells, such as those involved in building their protective walls.
Who could benefit from this research
Good fit: Patients suffering from multi-drug resistant bacterial infections could potentially benefit from future treatments developed through this foundational research.
Not a fit: Patients with conditions not related to bacterial infections would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to the discovery of entirely new antibiotic drugs that can overcome current drug resistance, offering hope for patients with difficult-to-treat bacterial infections.
How similar studies have performed: This research explores novel chemical applications and strategies for drug discovery, building on ongoing efforts in the field of small molecule chemistry and antibiotic development.
Where this research is happening
Memphis, United States
- University of Tennessee Health Sci Ctr — Memphis, United States (Active)
Researchers
- Principal investigator: Roy, Sudeshna — University of Tennessee Health Sci Ctr
- Study coordinator: Roy, Sudeshna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.