Finding new antibiotics from soil microbes
Official title: Redefining Fermentation Parameters in Natural Products Drug Discovery
Funded at Eastern Michigan University · NIH-10909043 · Data updated 2026-11-12
This study is looking for new antibiotics from soil bacteria to help fight infections that are becoming harder to treat, and it could lead to better options for patients dealing with antibiotic-resistant bacteria.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Eastern Michigan University NIH-funded |
| Lab location | 1 site (Ypsilanti, United States) |
| Project start | August 23, 2022 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $150,000 |
| NIH project number | 5R16AI167814-03 |
| Project ID | NIH-10909043 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from infections caused by antibiotic-resistant bacteria.
✕Less likely to help
Patients with infections that are not caused by bacterial pathogens or those who do not have antibiotic-resistant infections may not benefit from this research.
What this research studies
This research focuses on discovering new antibiotics from soil bacteria to combat the growing problem of antibiotic resistance. By utilizing advanced techniques in genomics and metabolomics, the project aims to identify and activate previously silent genetic pathways in bacteria that could lead to the production of novel antibiotics. Patients may benefit from new treatments that can effectively target resistant bacterial infections, which are becoming increasingly common. The research involves laboratory work with bacterial cultures and genetic analysis to uncover potential new drugs.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively treat infections resistant to current medications.
How similar studies have gone: Other research has successfully identified new antibiotics using similar genomic and metabolomic approaches, indicating a promising avenue for future discoveries.
Where this research is happening
-
Eastern Michigan University
Ypsilanti, United States Active
Researchers
- Principal investigator: Casper, Anne Marie — Eastern Michigan University
- Study coordinator: Casper, Anne Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.