Finding genetic factors linked to tooth decay in young children
Efficient methods for genome-wide survival analysis of early childhood caries
['FUNDING_R03'] · MICHIGAN STATE UNIVERSITY · NIH-10696112
This study is looking at how genes might play a role in causing tooth decay in young kids, with the goal of finding better ways to prevent and treat early childhood caries.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MICHIGAN STATE UNIVERSITY (nih funded) |
| Locations | 1 site (EAST LANSING, UNITED STATES) |
| Trial ID | NIH-10696112 on ClinicalTrials.gov |
What this research studies
This research investigates early childhood caries (ECC), a common chronic disease affecting preschool-age children in the U.S. The project aims to develop advanced statistical methods to analyze genetic data related to tooth decay, focusing on how genetic factors may influence the risk of developing ECC. By utilizing comprehensive data on tooth health over time, the researchers hope to identify genetic risk factors that contribute to this condition. This approach will enhance understanding of the genetic basis of ECC and improve strategies for prevention and treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are preschool-age children, particularly those with a family history of dental caries.
Not a fit: Patients who are older than 11 years or do not have a history of early childhood caries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and treatments for early childhood caries, ultimately improving dental health in young children.
How similar studies have performed: While there have been limited genome-wide association studies on early childhood caries, this research aims to introduce novel multi-locus survival analysis methods that have not been extensively tested in this context.
Where this research is happening
EAST LANSING, UNITED STATES
- MICHIGAN STATE UNIVERSITY — EAST LANSING, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LI, CHENXI — MICHIGAN STATE UNIVERSITY
- Study coordinator: LI, CHENXI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Chronic Disease, chronic disorder