Finding brain connectivity markers for mental health in adolescents

Identifying Transdiagnostic Functional Connectivity Biomarkers for Cognitive Health and Psychopathology

NIH-funded research Lehigh University · NIH-10830452

This study is looking at how the way different parts of the brain connect can help us spot early signs of thinking and mood problems in teenagers, using special technology to find patterns that could lead to better support for those who might be struggling.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionLehigh University NIH-funded
Lab location1 site (Bethlehem, United States)
Project IDNIH-10830452 on NIH RePORTER

What this research studies

This research investigates how brain connectivity patterns can serve as early indicators of cognitive dysfunction and psychiatric disorders in adolescents. By using advanced techniques like high-density electroencephalography (EEG), the study aims to identify biomarkers that cross traditional diagnostic boundaries, providing a more nuanced understanding of mental health issues. The approach combines machine learning methods to create predictive models that link brain connectivity features to individual cognitive behaviors, potentially leading to earlier interventions for those at risk. The goal is to enhance our understanding of how cognitive deficits relate to various psychiatric conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who may be experiencing cognitive deficits or symptoms of mental health disorders.

Not a fit: Patients outside the age range of 12 to 20 or those without cognitive or psychiatric symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and intervention strategies for adolescents at risk of developing psychiatric disorders.

How similar studies have performed: Previous research has shown promise in using brain connectivity markers for understanding psychiatric disorders, indicating that this approach could yield valuable insights.

Where this research is happening

Bethlehem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorderMental disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.