Finding a non-invasive way to detect endometriosis early
The non-invasive early detection of endometriosis
['FUNDING_R21'] · MAGEE-WOMEN'S RES INST AND FOUNDATION · NIH-10838470
This study is looking for a simple blood test that can help find endometriosis early, so women can get the care they need faster and with less discomfort than the current surgery.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAGEE-WOMEN'S RES INST AND FOUNDATION (nih funded) |
| Locations | 1 site (Pittsburgh, UNITED STATES) |
| Trial ID | NIH-10838470 on ClinicalTrials.gov |
What this research studies
This research aims to develop a non-invasive method for the early detection of endometriosis, a condition that causes significant pelvic pain and infertility in women. The approach focuses on analyzing cell-free DNA found in blood plasma to identify specific DNA methylation patterns associated with endometriosis. By targeting these genetic markers, the research seeks to provide a quicker and less invasive diagnostic option compared to the current surgical biopsy method, which often leads to delays in diagnosis and treatment. This could ultimately improve the quality of life for women suffering from this debilitating condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing symptoms of endometriosis, such as chronic pelvic pain or infertility.
Not a fit: Patients who do not exhibit symptoms of endometriosis or have already been diagnosed and treated may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of endometriosis, reducing pain and improving fertility outcomes for affected women.
How similar studies have performed: Other research has shown promise in using non-invasive methods for detecting various conditions through DNA analysis, suggesting that this approach could be viable for endometriosis as well.
Where this research is happening
Pittsburgh, UNITED STATES
- MAGEE-WOMEN'S RES INST AND FOUNDATION — Pittsburgh, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PETERS, DAVID GERARD — MAGEE-WOMEN'S RES INST AND FOUNDATION
- Study coordinator: PETERS, DAVID GERARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: chronic disorder, Chronic Disease, Disorder, Disease