Fighting antibiotic-resistant bacterial infections
Antibacterial Resistance Leadership Group (ARLG)
A national research network working to find better treatments and faster tests for people with serious bacterial infections, including antibiotic-resistant germs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11238540 on NIH RePORTER |
What this research studies
If I join this effort, I'd be part of a large national network led by experts at Duke that runs clinical trials and other studies across many hospitals. The team focuses on infections caused by Gram-negative and Gram-positive bacteria and works on improved diagnostics alongside new treatment strategies. Studies may enroll hospitalized patients with bloodstream or airway infections, collect samples, and compare different antibiotic approaches or rapid tests. The network partners with industry and uses centralized coordination to run trials and share results broadly.
Who could benefit from this research
Good fit: Ideal candidates are people hospitalized with serious bacterial infections (such as bloodstream or airway infections) or those whose infections are suspected to be antibiotic-resistant.
Not a fit: People without bacterial infections or those with only mild outpatient infections are unlikely to receive direct benefit from these trials.
Why it matters
Potential benefit: If successful, the work could lead to more effective antibiotics and faster tests that help clinicians treat resistant infections sooner.
How similar studies have performed: ARLG's prior work has already increased knowledge about antibiotic resistance and produced actionable findings that this renewed network will expand on.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Fowler, Vance G. — Duke University
- Study coordinator: Fowler, Vance G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.