Factory-treated long-lasting wraps to prevent malaria in young children
Official title: Factory-treated, long-lasting permethrin baby wraps for the prevention of malaria: A phase III randomized controlled trial
Funded at Mbarara University/science/ Technology · NIH-11358762 · Data updated 2026-11-12
A large study in Uganda will test whether factory-treated baby wraps that last up to a year can keep infants from getting malaria when used with bed nets.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mbarara University/science/ Technology NIH-funded |
| Lab location | 1 site (Mbarara, Uganda) |
| Project start | June 10, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $1,235,114 |
| NIH project number | 1R01AI199767-01 |
| Project ID | NIH-11358762 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are children around 3 months old in Uganda who will receive routine immunizations and their mothers who can commit to follow-up.
✕Less likely to help
Children not using wraps or living in areas outside the study sites may not experience the same benefit.
What this research studies
This study will enroll about 750 mother–infant pairs in Uganda and randomly assign them to receive either factory-treated permethrin wraps or untreated wraps, both with new dual-action bed nets. Families will be followed for up to a year to see how well the wraps prevent malaria and to monitor safety and any adverse effects. The trial uses a double-blind design so mothers and researchers don’t know which wraps are being used. Results could show a practical, long-lasting protection strategy against malaria in real-world settings.
Why it matters
Potential benefit: If successful, the factory-treated wraps could reduce malaria illness in young children without the need for frequent re-treatment.
How similar studies have gone: Previous results suggest a reduction in malaria incidence with permethrin-treated wraps, but long-lasting factory-treated textiles for broad use are being tested here.
Where this research is happening
-
Mbarara University/science/ Technology
Mbarara, Uganda Active
Researchers
- Principal investigator: Mulogo, Edgar — Mbarara University/science/ Technology
- Study coordinator: Mulogo, Edgar
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.