Exposure to violence in childhood and a specific asthma subtype in young Puerto Rican adults
Official title: Exposure to violence during childhood and Th2-high asthma in young Puerto Rican adults
Funded at University of Pittsburgh at Pittsburgh · NIH-11310002 · Data updated 2026-11-12
This project looks at how childhood violence affects a type of asthma (Th2-high) in young Puerto Rican adults and how mental health factors might influence it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | July 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $557,401 |
| NIH project number | 5R01HL168539-04 |
| Project ID | NIH-11310002 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are young Puerto Rican adults with asthma and a history of childhood exposure to violence or high violence-related distress.
✕Less likely to help
Individuals without asthma or without a history of childhood violence exposure may be less directly affected by the study outcomes.
What this research studies
The study follows young Puerto Rican adults to understand whether childhood exposure to violence and related distress are linked to a persistent Th2-high asthma endotype. It will examine biological samples, lung function, and symptom reports to map how psychosocial stressors relate to asthma biology over time. The research leverages prior findings in PR youth and extends them into early adulthood to identify mechanisms that sustain or worsen asthma. Participants may undergo assessments that could guide future prevention and treatment strategies tailored to this population.
Why it matters
Potential benefit: If successful, findings could lead to targeted prevention and treatment approaches for violence-linked asthma in young adults.
How similar studies have gone: Prior studies showed links between violence-related distress and asthma outcomes in youth; this work aims to confirm and extend those results into young adulthood.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Celedon, Juan Carlos — University of Pittsburgh at Pittsburgh
- Study coordinator: Celedon, Juan Carlos
Related research
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The link between childhood violence exposure and asthma in young Puerto Rican adults
This study looks at how experiencing violence as a child might affect asthma in young Puerto Rican adults, aiming to understand why some people have more severe asthma symptoms and how we can improve their treatment.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.