Exploring ways to fight antibiotic-resistant bacteria using the microbiome.
Microbiome Discovery and Mechanisms to Combat Antibiotic Resistance at Mucosal Surfaces
This study is exploring new ways to fight stubborn bacterial infections by using the good bacteria in our bodies and special viruses that target harmful germs, which could lead to safer and more effective treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11049071 on NIH RePORTER |
What this research studies
This research focuses on developing new methods to combat bacterial infections that are resistant to antibiotics by leveraging the body's microbiome. The approach involves studying how microbial communities can inhibit harmful pathogens and using bacteriophages to target specific bacteria without disrupting beneficial microbes. By maintaining the integrity of the native microbiome, this research aims to provide safer alternatives to traditional antibiotics. Patients may benefit from these innovative strategies that could lead to more effective treatments for infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from infections caused by antibiotic-resistant bacteria.
Not a fit: Patients with infections that are not caused by antibiotic-resistant bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that effectively manage antibiotic-resistant infections without harming beneficial bacteria.
How similar studies have performed: Other research has shown promise in using microbiome-based approaches and bacteriophages to combat bacterial infections, indicating a potential for success in this area.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Britton, Robert a — Baylor College of Medicine
- Study coordinator: Britton, Robert a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.